Antioxidant and free radical scavenging potential of. Download the complete microbiology project topic and material chapter 15 titled microbial profile of spoilt egusi citrullus colocynthis here on projects. Citrullus colocynthis cc, known as bitter apple, is used to treat diabetes in iranian traditional medicine. Preliminary phytochemical screening of the plant showed the presence of. Citrullus colocynthis pollen culture pollen grains which mostly remain attached in tetrads were germinated in sucrose solutions ranging from 2. Taking even very small amounts of colocynth can cause severe irritation of the stomach and intestine lining, bloody diarrhea, kidney damage, bloody urine, and inability to urinate. This study assessed the effects of these factors on the germination response of c. Citrullus colocynthis, with many common names including colocynth, bitter apple, bitter cucumber, desert gourd, citation needed egusi, vine of sodom, or wild gourd, is a desert viny plant native to the mediterranean basin and asia, especially turkey especially in regions such as izmir, and nubia it resembles a common watermelon vine, but bears small, hard fruits with a.
Several studies on this plant reported and focused on the biological and toxicological profile of fruits pulp. Phytochemical investigation, antioxidant and wound healing. Toxic effect of citrullus colocynthis on liver ijpt. Department of zoology, agrawal college, jaipur 3bbd college, chimanpura, jaipur. Citrullus colocynthis seeds as a potential source of protein for food. Germination response to light and temperature has been attributed to day length and temperature during seed maturation. If the inline pdf is not rendering correctly, you can download the pdf file here. Seeds of citrullus colocynthis are a rich source of fatty acids such as palmitic acid, stearic acid, oleic acid, linolenic acid and linoleic acid. Memorial college of pharmacy, jodhpur342001, rajasthan, india. Learn more about colocynth uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain colocynth. Citrullus colocynthis is a desert plant that requires arid and sandy soils and is found native to asia and mediterranean basin and also distributed in west coast of north africa. The objective of this study was to survey and identify c. The proposed theory is phytosomes of crude drug extract of citrullus colocynthis will be more effective and safe as an antidiabetic agent.
The three other species in the genus citrullus are the perennial bittergourd citrullus colocynthis l. Joshi1,4 1reproductive toxicology unit, center for advanced studies, department of zoology 2p. Despite its promise for the food industry, it is the smallscale, subsistence use that most concerns us here. Citrullus colocynthis colocynth, bitter apple, bitter gourd. Seed husk using the distributed activation energy model.
Topical antiinflammatory and analgesic activities of. Colocynth citrullus colocynthis uses, dosage, side effects. In iran, it grows in the southwest, southeast, central and eastern regions. The present study was performed to determine the efficacy of citrullus colocynthis on cutaneous leishmaniasis lesion in human. Publisher macmillan press year 1992 isbn 0333474945 description excellent and very comprehensive, though it contains a number of silly mistakes. Pdf medicinal utility of melon citrullus colocynthis l. Sufficient amount of citrullus colocynthis fruits were prepared and dissolved in 80 methnol and prepared in ointment baseat 80% concentration. Contraceptive efficacy of citrullus colocynthis methanolic. Citrullus colocynthis an overview sciencedirect topics.
See below for the abstract, table of contents, list of figures, list of tables, list of appendices, list of abbreviations and chapter one. Citrullus colocynthis is a very droughttolerant medicinal species, closely related to watermelon. We designed a pilot clinical trial to evaluate the safety and efficacy of topical c. Citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while reducing blood glucose and improving lipid levels. Chemical constituents and pharmacological effects of. Fruits of the plant contain bitter glycoside and those are used as drug for several purposes.
Based on the above findings, the researchers agreed that citrullus colocynthis is suitable for use as an antiinflammatory agent. If you experience drowsiness, dizziness, hypotension or a headache as sideeffects when using citrullus colocynthis medicine then it may not be safe to drive a vehicle or operate heavy machinery. The collected plants were maintained in the department green house at kakatiya university. Thermogravimetric and kinetic analysis of melon citrullus. Contraceptive efficacy of citrullus colocynthis methanolic extract in male rats aksha sharma1, priyanka sharma2, mridula chaturvedi3 and suresh c. It was banned by the food and drug administration fda in 1991. Citrullus colocynthis seeds as a potential source of protein for food and feed. Citrullus colocynthis as the cause of acute rectorrhagia.
Pdf the clinical investigation of citrullus colocynthis. Four patients with colocynth intoxication are presented. Citrullus colocynthis is a folk medicinal plant of saudi arabia. The word citrullus is the diminutive of the greek word citrus. Cucurbitaceae is a valuable plant widely distributed cucurbitaceae is a valuable plant widely distributed in the. We do not use these to store personal information about you. Citrullus colocynthis plants were used in the present investigation and seeds were collected from river valleys of koonoor warangal, andhra pradesh, basara nizamabad telangana state and bharathidasan university, thiruchunapally, tamilnadu, india. Antiobesity and antihyperlipidemic effect of citrullus colocynthis oil in the offspring of obese rats radjaa kaouthar meziane, latifa khemmar, fouzia amamou, mohamed yazit, amel didi, daoudi chabanesari laboratory of natural products in department of biology, university of tlemcen, tlemcen, algeria. Antiobesity and antihyperlipidemic effect of citrullus. Maximum germination was obtained in 5 per cent sucrose and the pollen tubes reached a length of. Effect of maturation conditions on light and temperature. Citrullus colocynthis fruits are generally documented for its broad range of pharmaceutical uses as well as medicinal and.
Safety evaluation studies of citrullus colocynthis for. Citrullus colocynthis contained carbohydrate, protein, separated amino acid, tannins, saponins. Liver gallbladder hp belladonna, carduus marianus, chelidonium majus, colocynthis, lycopodium clavatum, natrum sulphuricum, nux vomica, phosphorus, pulsatilla, veratrum album liquid if this spl contains inactivated ndcs listed by the fda initiated compliance action, they will be specified as such. The present study focused on the cytotoxic and genotoxic potency of aqueous leaves extract of this plant. Citrullus colocynthis fruits are usually recognized for its wide received in revised form range of medicinal uses as well as pharmaceutical and nutraceutical. Effects of an extracted lectin from citrullus colocynthis. The main clinical feature was acute rectorrhagia preceeded by mucosal diarrhea with tenesmus, which gradually progressed to bloody diarrhea and overt rectorrhagia within 3 to 4 hours. The present investigation was under taken to evaluate the antiasthmatic activity of ethanolic extract of citrullus colocynthis. Resistance to papaya ringspot viruswatermelon strain. Citrullus colocynthis supplement health benefits, dosage. Characterization of watermelon citrullus lanatus var.
The clinical investigation of citrullus colocynthis l. Cucurbitaceae is a medicinal plant traditionally used as an abortifacient and to treat constipation, oedema, bacterial infections, cancer and diabetes. Documents about citrullus colocynthis citco this website uses cookies our website uses cookies to ensure that we give you the best possible online experience. Citrullus colocynthis, cucurbitaceae, indravaruni, bitter apple. Click the download now button to get the complete project work instantly. The fruits of citrullus colocynthis have traditionally been used for the treatment of diseases such as diabetes. As already mentioned, that flour enriches and thickens soups as well as other foods.
Schrad is a valuable plants from cucurbitaceae family, widely distributed in the barren region, is a nonhardy, herbaceous perennial vine, branched from the base 4. Seed germination of citrullus colocynthis, as in many other species of cucurbitaceae, is inhibited by light, particularly at low temperatures. Watermelon, wild watermelon, egusi melon, west african watermelon, dessert watermelon, cooking melon, fodder melon, preserving melon, citron, melancia portuguese, pasteque french 1,6,8,9 etymology. The bitter desert watermelon, citrullus colocynthis l. In this article morphological and biological activity, inputs have been extensively recorded and discussed. The citrullus colocynthis extract significantly lowered the formation of granuloma tissue in chronic inflammation model. A genetic linkage map for watermelon derived from a.
Citrullus is a xerophytic genus native to africa and is diploid, with 11 pairs of chromosomes 2n 22. The carrageenaninduced edema in a rat hind paw was carried out to evaluate the topical anti. Efficacy of topical citrullus colocynthis bitter apple. The study indicates that the methanol extract of citrullus colocynthis fruit pulp when applied topically may promote. Cucurbitaceae, also known as bitter apple, a wellknown plant of ancient medical science, is a desert plant found in africa, the middle east and asia. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your bloodpressure extensively. Thermogravimetric and kinetic analysis of melon citrullus colocynthis l. Its botanical name is citrullus colocynthis and it belongs to cucurbitacae family. The aim of this study is to evaluate the antiinflammatory and analgesic activities of cc cream in rats. These materials flower stalks of the male, female, midrib, petiole and the tendril were fixed in faa, wax embedded, sectioned, stained and photographed with leitz diaplan photomicroscope fitted with leica wild mps 52 camera.
Pharmacists also advise patients not to drink alcohol with. Other side effects include convulsions, paralysis, and death. Evaluation of antiasthmatic activity of citrullus colocynthis fruit chandan genwa, umesh k. Citrullus colocynthis citcodocuments eppo global database. Metabolite profiling of citrullus colocynthis identified 70 chemically diverse. The fruit pulp of colocynth has medicinal properties while the seeds have nutritive qualities. Antioxidant and free radical scavenging potential of citrullus colocynthis l.
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